Obesity is a above claiming for bodies with schizophrenia.
We adjourned whether STEPWISE, a theory-based, accumulation structured affairs apprenticeship programme could abutment weight abridgement in bodies with schizophrenia.
In this randomised controlled balloon (study registration: ISRCTN19447796), we recruited adults with schizophrenia, schizoaffective ataxia or first-episode psychosis from ten brainy bloom organisations in England. Participants were about allocated to the STEPWISE action or analysis as usual. The 12-month action comprised four 2.5 h account accumulation sessions, followed by 2-weekly aliment acquaintance and accumulation sessions at 4, 7 and 10 months. The primary aftereffect was weight change afterwards 12 months. Key accessory outcomes included diet, concrete activity, biomedical measures and patient-related aftereffect measures. Cost-effectiveness was adjourned and a mixed-methods action appraisal was included.
Between 10 March 2015 and 31 March 2016, we recruited 414 bodies (intervention 208, accepted affliction 206) with 341 (84.4%) participants commutual the trial. At 12 months, weight abridgement did not alter amid groups (mean aberration 0.0 kg, 95% CI −1.6 to 1.7, P = 0.963); concrete activity, comestible assimilation and biochemical measures were unchanged. STEPWISE was well-received by participants and facilitators. The healthcare angle incremental cost-effectiveness arrangement was £246 921 per quality-adjusted life-year gained.
Participants were auspiciously recruited and retained, advertence a able absorption in weight interventions; however, the STEPWISE action was neither clinically
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